Unleashing the power of our science on the challenge of environmental sustainability has driven:

• The development of effective decision-making tools

• Selective investment in contemporary manufacturing technologies

• Reduction in time to market

Pharmaceuticals in the environment

The presence of pharmaceuticals in the environment and the issue of antimicrobial resistance (AMR) are important concerns for our industry. At Pfizer, we are committed to reducing the release of active pharmaceutical ingredients (APIs) into wastewater. The ingredients can include waste from the manufacture of antibiotics, which contain high levels of APIs. When these are released into the environment, the bacteria may be affected and there is a risk of antimicrobial resistance. To mitigate this risk, we follow best practices as outlined by the AMR Industry Alliance's (AMRIA) Antibiotic Manufacturing Standard. We are also testing new ways to manage and treat wastewater at some of our sites to improve our practices even futher.

Minimising Waste

One of the most important parts of our sustainable medicines programme is reducing waste across all our sites around the world. We constantly look for ways to improve our research, development, and manufacturing processes. This includes using green chemistry - which focuses on trying to redesign processes, and products, to reduce the use and generation of hazadous substances - and other sustainable practices. We encourage our sites to find ways to reduce, reuse, repurpose, and recycle materials like packaging and plastics. We have a system in place to help us make decisions about waste based on a hierarchy of control principles: avoid, reduce, reuse, recycle, and dispose.

Protecting Clean Water

We have assessed the water quality, scarcity, and availability risks at all of our Pfizer sites worldwide. We are developing plans to address any issues and protect water resources. These plans include measuring our water use, finding ways to conserve water, improving wastewater treatment, and working with local communities. We are also encouraging our suppliers in areas with water scarcity to develop similar plans.

Preserving Nature and Biodiversity

We understand the importance of nature and biodiversity, and we want to make sure we are doing our part to protect them. Some of our sites have teams dedicated to biodiversity that work with local communities to restore habitats and preserve biodiversity. In 2023, we launched an initiative to increase native biodiversity on sites that are being renovated or built. We work with ecologists to develop strategies for improving biodiversity and habitats.